CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.590 | Creatine Kinase; Chain A, domain 2 |
|
3.30.590.20 |
Domain Context
CATH Clusters
| Superfamily | 3.30.590.20 |
| Functional Family | Glutamate--cysteine ligase |
Enzyme Information
| 6.3.2.2 |
Glutamate--cysteine ligase.
based on mapping to UniProt P0A6W9
ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L- cysteine.
-!- Can use L-aminohexanoate in place of glutamate.
|
UniProtKB Entries (1)
| P0A6W9 |
GSH1_ECOLI
Escherichia coli K-12
Glutamate--cysteine ligase
|
PDB Structure
| PDB | 1V4G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis
PROC.NATL.ACAD.SCI.USA
|
