CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Cyclin-dependent-like kinase 5

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q00535
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q00535
CDK5_HUMAN
Homo sapiens
Cyclin-dependent-like kinase 5

PDB Structure

PDB 1UNL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanism of Cdk5/P25 Binding by Cdk Inhibitors
Mapelli, M., Massimilinao, L., Crovace, C., Seeliger, M.A., Tsai, L.-H., Meijer, L., Musacchio, A.
J.Med.Chem.