CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 3.2.1.122 |
Maltose-6'-phosphate glucosidase.
based on mapping to UniProt P54716
Alpha-maltose 6'-phosphate + H(2)O = D-glucose + D-glucose 6-phosphate.
-!- Hydrolyzes a variety of 6-phospho-alpha-D-glucosides, including alpha-maltose 6-phosphate, alpha,alpha-trehalose 6-phosphate, sucrose 6-phosphate and p-nitrophenyl-alpha-D-glucopyranoside 6-phosphate (as a chromogenic substrate). -!- The enzyme is activated by Fe(2+), Mn(2+), Co(2+) and Ni(2+). -!- It is rapidly inactivated in air.
|
UniProtKB Entries (1)
| P54716 |
GLVA_BACSU
Bacillus subtilis subsp. subtilis str. 168
Maltose-6'-phosphate glucosidase
|
PDB Structure
| PDB | 1U8X |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Novel Catalytic Mechanism of Glycoside Hydrolysis Based on the Structure of an NAD(+)/Mn(2+)-Dependent Phospho-alpha-Glucosidase from Bacillus subtilis.
STRUCTURE
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