CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P45481
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

P45481
CBP_MOUSE
Mus musculus
CREB-binding protein

PDB Structure

PDB 1U2N
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding
De Guzman, R.N., Wojciak, J.M., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.
Biochemistry