CATH Classification

Domain Context

CATH Clusters

Superfamily Dbl homology (DH) domain
Functional Family Rho guanine nucleotide exchange factor (GEF) 11

Enzyme Information

UniProtKB Entries (1)

Q9NZN5
ARHGC_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 12

PDB Structure

PDB 1TXD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Kristelly, R., Gao, G., Tesmer, J.J.
J.Biol.Chem.