CATH Classification

Domain Context

CATH Clusters

Superfamily Serine-tRNA synthetase, tRNA binding domain
Functional Family

Enzyme Information

6.1.1.11
Serine--tRNA ligase.
based on mapping to UniProt P34945
(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
-!- This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.

UniProtKB Entries (1)

P34945
SYS_THET2
Thermus thermophilus HB27
Serine--tRNA ligase

PDB Structure

PDB 1SRY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution.
Fujinaga, M., Berthet-Colominas, C., Yaremchuk, A.D., Tukalo, M.A., Cusack, S.
J.Mol.Biol.