CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2000 | Glycogen Phosphorylase B; |
Domain Context
CATH Clusters
| Superfamily | Glycogen Phosphorylase B; |
| Functional Family | Glycosyltransferase GtfE |
Enzyme Information
| 2.4.1.322 |
Devancosaminyl-vancomycin vancosaminetransferase.
based on mapping to UniProt Q9AFC7
dTDP-beta-L-vancosamine + devancosaminyl-vancomycin = dTDP + vancomycin.
-!- The enzyme, isolated from the bacterium Amycolatopsis orientalis, catalyzes the ultimate step in the biosynthesis of the antibiotic vancomycin.
|
UniProtKB Entries (1)
| Q9AFC7 |
GTFD_AMYOR
Amycolatopsis orientalis
Devancosaminyl-vancomycin vancosaminetransferase
|
PDB Structure
| PDB | 1RRV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
Biochemistry
|