CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.970 | Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 |
|
1.20.970.30 | eIF4G, eIF4E-binding domain |
Domain Context
CATH Clusters
| Superfamily | eIF4G, eIF4E-binding domain |
| Functional Family | Translation initiation factor eIF4G |
Enzyme Information
UniProtKB Entries (1)
| P39935 |
IF4F1_YEAST
Saccharomyces cerevisiae S288C
Eukaryotic initiation factor 4F subunit p150
|
PDB Structure
| PDB | 1RF8 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell(Cambridge,Mass.)
|