CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.718 | Isopropylmalate Dehydrogenase |
|
3.40.718.10 | Isopropylmalate Dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | Isopropylmalate Dehydrogenase |
| Functional Family | 4-hydroxythreonine-4-phosphate dehydrogenase |
Enzyme Information
| 1.1.1.262 |
4-hydroxythreonine-4-phosphate dehydrogenase.
based on mapping to UniProt P58717
4-phosphooxy-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO(2) + NADH.
-!- The enzyme is part of the biosynthesis pathway of the coenzyme pyridoxal 5'-phosphate found in anaerobic bacteria.
|
UniProtKB Entries (1)
| P58717 |
PDXA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
4-hydroxythreonine-4-phosphate dehydrogenase
|
PDB Structure
| PDB | 1R8K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of NAD-dependent dehydrogenase/carboxylase of Salmonella typhimurium
to be published
|