CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.60.20
Functional Family Diacylglycerol kinase

Enzyme Information

2.7.1.107
Diacylglycerol kinase (ATP).
based on mapping to UniProt Q16760
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
-!- Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. -!- Activity is stimulated by certain phospholipids. -!- In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. -!- cf. EC 2.7.1.174.

UniProtKB Entries (1)

Q16760
DGKD_HUMAN
Homo sapiens
Diacylglycerol kinase delta

PDB Structure

PDB 1R79
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta
Miyamoto, K., Tomizawa, T., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S.
To be Published