CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.290 |
Domain Context
CATH Clusters
| Superfamily | 2.40.50.290 |
| Functional Family | Glycyl-glycine endopeptidase LytM |
Enzyme Information
| 3.4.24.75 |
Lysostaphin.
based on mapping to UniProt O33599
Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans.
-!- Lyses cells of Staphylococcus aureus in particular, by its action on the cross-bridge of the cell wall. -!- Belongs to peptidase family M23.
|
UniProtKB Entries (1)
| O33599 |
LYTM_STAA8
Staphylococcus aureus subsp. aureus NCTC 8325
Glycyl-glycine endopeptidase LytM
|
PDB Structure
| PDB | 1QWY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Latent LytM at 1.3A resolution.
J.Mol.Biol.
|
