CATH Domain 1qmnA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Serine protease inhibitor

Enzyme Information

UniProtKB Entries (1)

AACT_HUMAN

Homo sapiens

Alpha-1-antichymotrypsin

PDB Structure

PDB	1QMN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two-Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease Gooptu, B., Hazes, B., Chang, W.-S.W., Dafforn, T.R., Carrell, R.W., Read, R.J., Lomas, D.A. Proc.Natl.Acad.Sci.USA