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1 keywords

CATH Domain 1qdsA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Triosephosphate isomerase

Enzyme Information

5.3.1.1
Triose-phosphate isomerase.
based on mapping to UniProt P48499
D-glyceraldehyde 3-phosphate = glycerone phosphate.

UniProtKB Entries (1)

P48499
TPIS_LEIME
Leishmania mexicana
Triosephosphate isomerase

PDB Structure

PDB 1QDS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase.
Lambeir, A.M., Backmann, J., Ruiz-Sanz, J., Filimonov, V., Nielsen, J.E., Kursula, I., Norledge, B.V., Wierenga, R.K.
Eur.J.Biochem.
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