CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.20 | Single Sheet |
|
2.20.25 | N-terminal domain of TfIIb |
|
2.20.25.180 |
Domain Context
CATH Clusters
| Superfamily | 2.20.25.180 |
| Functional Family |
Enzyme Information
| 2.7.7.- |
Nucleotidyltransferases.
based on mapping to UniProt P03692
|
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt P03692
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| P03692 |
PRIM_BPT7
Enterobacteria phage T7
DNA primase/helicase
|
PDB Structure
| PDB | 1Q57 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell
|