×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Sterol 3-beta-glucosyltransferase UGT80A2

Enzyme Information

2.4.1.311
dTDP-epi-vancosaminyltransferase.
based on mapping to UniProt P96558
dTDP-beta-L-4-epi-vancosamine + devancoaminyl-vancomycin = dTDP + chloroorienticin B.
-!- The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of the glycopeptide antibiotic chloroeremomycin.

UniProtKB Entries (1)

P96558
GTFA_AMYOR
Amycolatopsis orientalis
DTDP-epi-vancosaminyltransferase

PDB Structure

PDB 1PNV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Mulichak, A.M., Losey, H.C., Lu, W., Wawrzak, Z., Walsh, C.T., Garavito, R.M.
Proc.Natl.Acad.Sci.USA
CATH-Gene3D is a Global Biodata Core Resource Learn more...