CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Glutamate decarboxylase

Enzyme Information

4.1.1.15
Glutamate decarboxylase.
based on mapping to UniProt P69910
L-glutamate = 4-aminobutanoate + CO(2).
-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.

UniProtKB Entries (1)

P69910
DCEB_ECOLI
Escherichia coli K-12
Glutamate decarboxylase beta

PDB Structure

PDB 1PMO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure and functional analysis of escherichia coli glutamate decarboxylase
Capitani, G., De Biase, D., Aurizi, C., Gut, H., Bossa, F., Grutter, M.G.
Embo J.