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CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family Mitochondrial aldehyde dehydrogenase 2

Enzyme Information

1.2.1.3
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt Q28399
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.

UniProtKB Entries (1)

Q28399
ALDH1_ELEED
Elephantulus edwardii
Aldehyde dehydrogenase, cytosolic 1

PDB Structure

PDB 1O9J
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Eta-Crystallin: Adaptation of a Class 1 Aldehyde Dehydrogenase for a New Role in the Eye Lens
Bateman, O.A., Purkiss, A.G., Van Montfort, R., Slingsby, C., Graham, C., Wistow, G.
Biochemistry
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