CATH Domain 1o20A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.309	Aldehyde Dehydrogenase; Chain A, domain 2
	3.40.309.10	Aldehyde Dehydrogenase; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily	Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family	Gamma-glutamyl phosphate reductase

Enzyme Information

1.2.1.41

Glutamate-5-semialdehyde dehydrogenase.

based on mapping to UniProt Q9WYC9

L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH.

UniProtKB Entries (1)

PROA_THEMA

Thermotoga maritima MSB8

Gamma-glutamyl phosphate reductase

PDB Structure

PDB	1O20
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution. Page, R., Nelson, M.S., von Delft, F., Elsliger, M.A., Canaves, J.M., Brinen, L.S., Dai, X., Deacon, A.M., Floyd, R., Godzik, A., Grittini, C., Grzechnik, S.K., Jaroszewski, L., Klock, H.E., Koesema, E., Kovarik, J.S., Kreusch, A., Kuhn, P., Lesley, S.A., McMullan, D., McPhillips, T.M., Miller, M.D., Morse, A., Moy, K., Ouyang, J., Robb, A., Rodrigues, K., Schwarzenbacher, R., Spraggon, G., Stevens, R.C., van den Bedem, H., Velasquez, J., Vincent, J., Wang, X., West, B., Wolf, G., Hodgson, K.O., Wooley, J., Wilson, I.A. Proteins