CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.30 | Luciferase-like domain |
Domain Context
CATH Clusters
| Superfamily | Luciferase-like domain |
| Functional Family | Alkanesulfonate monooxygenase |
Enzyme Information
| 1.14.14.5 |
Alkanesulfonate monooxygenase.
based on mapping to UniProt P80645
An alkanesulfonate (R-CH(2)-SO(3)H) + FMNH(2) + O(2) = an aldehyde (R-CHO) + FMN + sulfite + H(2)O.
-!- The enzyme from Escherichia coli catalyzes the desulfonation of a wide range of aliphatic sulfonates (unsubstituted C(1)- to C(14)- sulfonates as well as substituted C(2)-sulfonates). -!- Does not desulfonate taurine (2-aminoethanesulfonate) or aromatic sulfonates. -!- Does not use FMN as a bound cofactor. -!- Instead, it uses reduced FMN (i.e., FMNH(2)) as a substrate. -!- FMNH(2) is provided by SsuE, the associated FMN reductase (EC 1.5.1.38).
|
UniProtKB Entries (1)
| P80645 |
SSUD_ECOLI
Escherichia coli K-12
Alkanesulfonate monooxygenase
|
PDB Structure
| PDB | 1NQK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of the protein
Alkanesulfonate monooxygenase from E. Coli
To be Published
|