CATH Classification

Domain Context

CATH Clusters

Superfamily DnaJ domain
Functional Family putative tyrosine-protein phosphatase auxilin isoform X2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q27974
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q27974
AUXI_BOVIN
Bos taurus
Putative tyrosine-protein phosphatase auxilin

PDB Structure

PDB 1N4C
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structure of the functional fragment of auxilin required for catalytic uncoating of clathrin-coated vesicles.
Gruschus, J.M., Han, C.J., Greener, T., Ferretti, J.A., Greene, L.E., Eisenberg, E.
Biochemistry