×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily RNA-directed RNA polymerase lambda-3
Functional Family

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt P0CK31
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.

UniProtKB Entries (1)

P0CK31
RDRP_REOVD
Mammalian orthoreovirus 3 Dearing
RNA-directed RNA polymerase lambda-3

PDB Structure

PDB 1N38
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Tao, Y., Farsetta, D.L., Nibert, M.L., Harrison, S.C.
Cell(Cambridge,Mass.)
CATH-Gene3D is a Global Biodata Core Resource Learn more...