CATH Classification

Domain Context

CATH Clusters

Superfamily Endonuclease Chain A
Functional Family Tyrosyl-DNA phosphodiesterase 1

Enzyme Information

3.1.4.-
Phosphoric diester hydrolases.
based on mapping to UniProt Q9NUW8

UniProtKB Entries (1)

Q9NUW8
TYDP1_HUMAN
Homo sapiens
Tyrosyl-DNA phosphodiesterase 1

PDB Structure

PDB 1MU7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J.
J.Mol.Biol.