×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily R3H-like domain
Functional Family Immunoglobulin mu DNA-binding protein 2

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P38935
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
3.6.4.12
DNA helicase.
based on mapping to UniProt P38935
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).

UniProtKB Entries (1)

P38935
SMBP2_HUMAN
Homo sapiens
DNA-binding protein SMUBP-2

PDB Structure

PDB 1MSZ
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of the R3H domain from human Smubp-2
Liepinsh, E., Leonchiks, A., Sharipo, A., Guignard, L., Otting, G.
J.Mol.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...