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1 keywords

CATH Domain 1ml9A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.170 Beta Complex
Topology 2.170.270 Beta-clip-like
Homologous Superfamily 2.170.270.10 SET domain

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8X225
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8X225
DIM5_NEUCR
Neurospora crassa OR74A
Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5

PDB Structure

PDB 1ML9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
Zhang, X., Tamaru, H., Khan, S.I., Horton, J.R., Keefe, L.J., Selker, E.U., Cheng, X.
Cell(Cambridge,Mass.)
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