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1 keywords

CATH Domain 1mb2A01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P00953
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P00953
SYW_GEOSE
Geobacillus stearothermophilus
Tryptophan--tRNA ligase

PDB Structure

PDB 1MB2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
Retailleau, P., Huang, X., Yin, Y., Hu, M., Weinreb, V., Vachette, P., Vonrhein, C., Bricogne, G., Roversi, P., Ilyin, V., Carter, C.W.
J.Mol.Biol.
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