CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate-binding domains
Functional Family 3-methyl-2-oxobutanoate hydroxymethyltransferase

Enzyme Information

2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase.
based on mapping to UniProt P31057
5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O = tetrahydrofolate + 2-dehydropantoate.

UniProtKB Entries (1)

P31057
PANB_ECOLI
Escherichia coli K-12
3-methyl-2-oxobutanoate hydroxymethyltransferase

PDB Structure

PDB 1M3U
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of E. coli Ketopantoate Hydroxymethyl Transferase Complexed with Ketopantoate and Mg(2+), Solved by Locating 160 Selenomethionine Sites.
von Delft, F., Inoue, T., Saldanha, S.A., Ottenhof, H.H., Schmitzberger, F., Birch, L.M., Dhanaraj, V., Witty, M., Smith, A.G., Blundell, T.L., Abell, C.
Structure