CATH Domain 1lp4A02
|1.10.510||Transferase(Phosphotransferase); domain 1|
|1.10.510.10||Transferase(Phosphotransferase) domain 1|
|Superfamily||Transferase(Phosphotransferase) domain 1|
|Functional Family||Casein kinase II subunit alpha|
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P28523
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 220.127.116.11 and EC 18.104.22.168.
UniProtKB Entries (1)
Casein kinase II subunit alpha
Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate.