CATH Classification

Domain Context

CATH Clusters

Superfamily Dbl homology (DH) domain
Functional Family Guanine nucleotide exchange factor DBS

Enzyme Information

UniProtKB Entries (2)

Q64096
MCF2L_MOUSE
Mus musculus
Guanine nucleotide exchange factor DBS
P61586
RHOA_HUMAN
Homo sapiens
Transforming protein RhoA

PDB Structure

PDB 1LB1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Snyder, J.T., Worthylake, D.K., Rossman, K.L., Betts, L., Pruitt, W.M., Siderovski, D.P., Der, C.J., Sondek, J.
Nat.Struct.Biol.