CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.900 | Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A |
|
3.30.900.10 | HORMA domain |
Domain Context
CATH Clusters
| Superfamily | HORMA domain |
| Functional Family | Mitotic spindle assembly checkpoint protein MAD2A |
Enzyme Information
UniProtKB Entries (1)
| Q13257 |
MD2L1_HUMAN
Homo sapiens
Mitotic spindle assembly checkpoint protein MAD2A
|
PDB Structure
| PDB | 1KLQ |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.
Mol.Cell
|