CATH Domain 1ki6B00
|22.214.171.1240||P-loop containing nucleotide triphosphate hydrolases|
|Superfamily||P-loop containing nucleotide triphosphate hydrolases|
based on mapping to UniProt P03176
ATP + thymidine = ADP + thymidine 5'-phosphate.
-!- Deoxyuridine can also act as acceptor. -!- dGTP can also act as donor. -!- The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyzes this reaction as well as those of EC 126.96.36.199, EC 188.8.131.52 and EC 184.108.40.206. -!- Formerly EC 220.127.116.11.
UniProtKB Entries (1)
Human alphaherpesvirus 1 strain 17
Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.