CATH Domain 1ki6A00
|18.104.22.1680||P-loop containing nucleotide triphosphate hydrolases|
|Superfamily||P-loop containing nucleotide triphosphate hydrolases|
based on mapping to UniProt P03176
ATP + thymidine = ADP + thymidine 5'-phosphate.
-!- Deoxyuridine can also act as acceptor. -!- dGTP can also act as donor. -!- The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyzes this reaction as well as those of EC 22.214.171.124, EC 126.96.36.199 and EC 188.8.131.52. -!- Formerly EC 184.108.40.206.
UniProtKB Entries (1)
Human alphaherpesvirus 1 strain 17
Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.