CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate Carboxykinase, domain 1
Functional Family Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

Enzyme Information

4.1.1.32
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P35558
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.

UniProtKB Entries (1)

P35558
PCKGC_HUMAN
Homo sapiens
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

PDB Structure

PDB 1KHB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
Dunten, P., Belunis, C., Crowther, R., Hollfelder, K., Kammlott, U., Levin, W., Michel, H., Ramsey, G.B., Swain, A., Weber, D., Wertheimer, S.J.
J.Mol.Biol.