CATH Domain 1kgqA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.166	Tetrahydrodipicolinate-N-succinyltransferase; Chain A, domain 1
	1.10.166.10	Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain

Domain Context

CATH Clusters

Superfamily	Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain
Functional Family	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Enzyme Information

2.3.1.117

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase.

based on mapping to UniProt P56220

Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.

-!- Involved in the biosynthesis of lysine in bacteria, cyanobacteria and higher plants. -!- Earlier erroneously called 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase.

UniProtKB Entries (1)

P56220

DAPD_UNKP

unidentified prokaryotic organism

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

PDB Structure

PDB	1KGQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. Beaman, T.W., Vogel, K.W., Drueckhammer, D.G., Blanchard, J.S., Roderick, S.L. Protein Sci.