CATH Domain 1k9oE01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Anionic trypsin-2

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00763

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00763	TRY2_RAT Rattus norvegicus Anionic trypsin-2
P14754	SERA_MANSE Manduca sexta Alaserpin

PDB Structure

PDB	1K9O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The structure of a Michaelis serpin-protease complex. Ye, S., Cech, A.L., Belmares, R., Bergstrom, R.C., Tong, Y., Corey, D.R., Kanost, M.R., Goldsmith, E.J. Nat.Struct.Biol.