CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P14489
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P14489
BLO10_PSEAI
Pseudomonas aeruginosa
Beta-lactamase OXA-10

PDB Structure

PDB 1K55
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases.
Golemi, D., Maveyraud, L., Vakulenko, S., Samama, J.P., Mobashery, S.
Proc.Natl.Acad.Sci.USA