CATH Classification

Domain Context

CATH Clusters

Superfamily Isoleucyl-tRNA Synthetase; Domain 1
Functional Family

Enzyme Information

6.1.1.5
Isoleucine--tRNA ligase.
based on mapping to UniProt P56690
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).

UniProtKB Entries (1)

P56690
SYI_THET8
Thermus thermophilus HB8
Isoleucine--tRNA ligase

PDB Structure

PDB 1JZQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase.
Nakama, T., Nureki, O., Yokoyama, S.
J.Biol.Chem.