CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate/ornithine carbamoyltransferase
Functional Family N-acetylornithine carbamoyltransferase

Enzyme Information

2.1.3.9
N-acetylornithine carbamoyltransferase.
based on mapping to UniProt Q8A1E9
Carbamoyl phosphate + N(2)-acetyl-L-ornithine = phosphate + N-acetyl-L- citrulline.
-!- Differs from EC 2.1.3.3. -!- This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate.

UniProtKB Entries (1)

Q8A1E9
AOTC_BACTN
Bacteroides thetaiotaomicron VPI-5482
N-acetylornithine carbamoyltransferase

PDB Structure

PDB 1JS1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution.
Shi, D., Gallegos, R., DePonte III, J., Morizono, H., Yu, X., Allewell, N.M., Malamy, M., Tuchman, M.
J.Mol.Biol.