CATH Classification

Domain Context

CATH Clusters

Superfamily L-arginine/glycine Amidinotransferase; Chain A
Functional Family Glycine amidinotransferase, mitochondrial

Enzyme Information

2.1.4.1
Glycine amidinotransferase.
based on mapping to UniProt P50440
L-arginine + glycine = L-ornithine + guanidinoacetate.
-!- Canavanine can act instead of arginine. -!- Formerly EC 2.6.2.1.

UniProtKB Entries (1)

P50440
GATM_HUMAN
Homo sapiens
Glycine amidinotransferase, mitochondrial

PDB Structure

PDB 1JDX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
Fritsche, E., Humm, A., Huber, R.
J.Biol.Chem.