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1 keywords

CATH Domain 1j7jB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Hypoxanthine phosphoribosyltransferase

Enzyme Information

2.4.2.8
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt O33799
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.

UniProtKB Entries (1)

O33799
HPRT_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Hypoxanthine phosphoribosyltransferase

PDB Structure

PDB 1J7J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of the HPRT from Salmonella Typhimurium at 2.3 A Resolution
Lee, C.C., Focia, P.J., Spraggon, G., Eakin, A.E.
To be Published
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