CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P00953
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P00953
SYW_GEOSE
Geobacillus stearothermophilus
Tryptophan--tRNA ligase

PDB Structure

PDB 1I6M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP.
Retailleau, P., Yin, Y., Hu, M., Roach, J., Bricogne, G., Vonrhein, C., Roversi, P., Blanc, E., Sweet, R.M., Carter, C.W.
Acta Crystallogr.,Sect.D