CATH Domain 1htjF00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.167	Regulator of G-protein Signalling 4; domain 2
	1.10.167.10	Regulator of G-protein Signalling 4, domain 2

Domain Context

CATH Clusters

Superfamily	Regulator of G-protein Signalling 4, domain 2
Functional Family	Rho guanine nucleotide exchange factor (GEF) 11

Enzyme Information

UniProtKB Entries (1)

ARHGB_HUMAN

Homo sapiens

Rho guanine nucleotide exchange factor 11

PDB Structure

PDB	1HTJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases. Longenecker, K.L., Lewis, M.E., Chikumi, H., Gutkind, J.S., Derewenda, Z.S. Structure