CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family |
Enzyme Information
| 3.4.21.82 |
Glutamyl endopeptidase II.
based on mapping to UniProt Q07006
Preferential cleavage: -Glu-|-Xaa- >> -Asp-|-Xaa-. Preference for Pro or Leu at P2 and Phe at P3. Cleavage of -Glu-|-Asp- and -Glu-|-Pro- bonds is slow.
-!- Inhibited by (18-Leu->Glu) modified turkey ovomucoid third domain. -!- Belongs to peptidase family S1E.
|
UniProtKB Entries (1)
| Q07006 |
GLUP_STRGR
Streptomyces griseus
Glutamyl endopeptidase 2
|
PDB Structure
| PDB | 1HPG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding.
Biochemistry
|