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1 keywords

CATH Domain 1hfbC00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Phospho-2-dehydro-3-deoxyheptonate aldolase

Enzyme Information

2.5.1.54
3-deoxy-7-phosphoheptulonate synthase.
based on mapping to UniProt P32449
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D- arabino-hept-2-ulosonate 7-phosphate + phosphate.
-!- Formerly EC 4.1.2.15.

UniProtKB Entries (1)

P32449
AROG_YEAST
Saccharomyces cerevisiae S288C
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

PDB Structure

PDB 1HFB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evolution of Feedback-Inhibited Beta /Alpha Barrel Isoenzymes by Gene Duplication and a Single Mutation
Hartmann, M., Schneider, T.R., Pfeil, A., Heinrich, G., Lipscomb, W., Braus, G.H.
Proc.Natl.Acad.Sci.USA
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