CATH Domain 1h56B00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.210	PvuII Endonuclease; Chain A
	3.40.210.10	PVUII Endonuclease, subunit A

Domain Context

CATH Clusters

Superfamily	PVUII Endonuclease, subunit A
Functional Family

Enzyme Information

3.1.21.4

Type II site-specific deoxyribonuclease.

based on mapping to UniProt P23657

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P23657

T2P2_PROHU

Proteus hauseri

Type-2 restriction enzyme PvuII

PDB Structure

PDB	1H56
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Biochemical Characterization of a New Mg(2+) Binding Site Near Tyr94 in the Restriction Endonuclease PvuII. Spyridaki, A., Matzen, C., Lanio, T., Jeltsch, A., Simoncsits, A., Athanasiadis, A., Scheuring-Vanamee, E., Kokkinidis, M., Pingoud, A. J.Mol.Biol.