CATH Domain 1gtdB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1280	Mth169; Chain: A ,
	3.30.1280.10	Phosphoribosylformylglycinamidine synthase subunit PurS

Domain Context

CATH Clusters

Superfamily	Phosphoribosylformylglycinamidine synthase subunit PurS
Functional Family

Enzyme Information

6.3.5.3

Phosphoribosylformylglycinamidine synthase.

based on mapping to UniProt O26271

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.

UniProtKB Entries (1)

O26271

PURS_METTH

Methanothermobacter thermautotrophicus str. Delta H

Phosphoribosylformylglycinamidine synthase subunit PurS

PDB Structure

PDB	1GTD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Mth169, a Crucial Component of Phosphoribosylformylglycinamidine Synthetase Batra, R., Christendat, D., Edwards, A., Arrowsmith, C., Tong, L. Proteins: Struct.,Funct., Genet.