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CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.72
Site-specific DNA-methyltransferase (adenine-specific).
based on mapping to UniProt P23192
S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA.
-!- This is a large group of enzymes, most of which form so-called 'restriction-modification systems', with nucleases that possess similar site specificity (the nucleases are listed as either EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5). -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P23192
MTM2_MORBO
Moraxella bovis
Modification methylase MboII

PDB Structure

PDB 1G60
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of MboIIA methyltransferase.
Osipiuk, J., Walsh, M.A., Joachimiak, A.
Nucleic Acids Res.
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