1 keywords

CATH Domain 1g5jA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.437 Apoptosis Regulator Bcl-x
Homologous Superfamily 1.10.437.10 Blc2-like

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family Bcl-2-like protein 1

Enzyme Information

UniProtKB Entries (1)

Q07817
B2CL1_HUMAN
Homo sapiens
Bcl-2-like protein 1

PDB Structure

PDB 1G5J
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.
Petros, A.M., Nettesheim, D.G., Wang, Y., Olejniczak, E.T., Meadows, R.P., Mack, J., Swift, K., Matayoshi, E.D., Zhang, H., Thompson, C.B., Fesik, S.W.
Protein Sci.