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1 keywords

CATH Domain 1g4iA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.90 Phospholipase A2
Homologous Superfamily 1.20.90.10 Phospholipase A2 domain

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P00593
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P00593
PA21B_BOVIN
Bos taurus
Phospholipase A2

PDB Structure

PDB 1G4I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structure of bovine pancreatic phospholipase A2 at atomic resolution.
Steiner, R.A., Rozeboom, H.J., de Vries, A., Kalk, K.H., Murshudov, G.N., Wilson, K.S., Dijkstra, B.W.
Acta Crystallogr.,Sect.D
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