CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 3 | Alpha Beta | 
|   | 3.40 | 3-Layer(aba) Sandwich | 
|   | 3.40.50 | Rossmann fold | 
|   | 3.40.50.10140 | Toll/interleukin-1 receptor homology (TIR) domain | 
Domain Context
CATH Clusters
| Superfamily | Toll/interleukin-1 receptor homology (TIR) domain | 
| Functional Family | Toll-like receptor 2 | 
Enzyme Information
UniProtKB Entries (1)
| Q15399 | TLR1_HUMAN Homo sapiens Toll-like receptor 1 | 
PDB Structure
| PDB | 1FYV | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | Escherichia | 
| Primary Citation | Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature | 
