CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.1400.10
Functional Family

Enzyme Information

3.5.1.11
Penicillin amidase.
based on mapping to UniProt P06875
Penicillin + H(2)O = a carboxylate + 6-aminopenicillanate.

UniProtKB Entries (1)

P06875
PAC_ECOLX
Escherichia coli
Penicillin G acylase

PDB Structure

PDB 1FXV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Alkema, W.B., Hensgens, C.M., Kroezinga, E.H., de Vries, E., Floris, R., van der Laan, J.M., Dijkstra, B.W., Janssen, D.B.
Protein Eng.